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Menopause Information Hub

Testosterone

Learn about testosterone and its role in menopause

Testosterone is a natural female hormone, just like oestrogen and progesterone. Levels are usually highest between the ages of 18 and 24. Our levels decline steadily with age and may be up to 70 per cent lower by the time of natural menopause.

Many women will not notice the reduction in testosterone levels over time and will have no need to replace this hormone. However, it can be the final missing piece of the jigsaw in menopause management for some and appears to be especially important in women with premature ovarian insufficiency (POI), early menopause and/or surgical menopause (removal of ovaries).

Testosterone replacement

The British Menopause Society advises that testosterone replacement in menopause can be considered should oestrogen alone fail to improve low libido. Some women also gain improvement in mental sharpness, energy levels and joie de vivre, but there is not enough evidence for testosterone to be formally recommended for these reasons in current guidelines.

Prior to starting testosterone replacement, low levels should be confirmed with a blood test. Blood levels will then need to be monitored at 3-6 months and then yearly after this. This is to ensure that testosterone levels stay within the normal female physiological range and reduces the risk of side effects.

Currently, there is no testosterone product available on the NHS licensed for female use. However, male-licensed products, such as Tostran and Testogel, can be used off licence in accordance with British Menopause Society guidelines. Alternatively, we can prescribe Androfeme testosterone privately. This is a body identical female testosterone cream which we import under a special licence from Australia.

Most testosterone products come as a cream or gel that is rubbed into the skin daily (transdermal preparations). They are very well tolerated and thought to be low risk. If used at the recommended doses, and with appropriate blood monitoring, side effects are minimal. Higher doses can sometimes lead to unwanted effects such as local hair growth at the application site, mild acne, and hair loss. These effects can be avoided/minimised with appropriate monitoring.

In exceptional circumstances, some women may be given testosterone via an implant, but these are not readily available across the UK (whether on the NHS or privately). Implants are usually reserved for younger women in surgical menopause who have not achieved any benefit from transdermal preparations.

If you are interested in trying testosterone replacement, please book a consultation with one of our Menopause Care specialists.

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