HRT - Oestrogen Spray

Oestrogen spray is a body identical oestrogen, derived from plants (yams), which is a spray onto the skin and is gradually absorbed. There is one option of oestrogen spray which is Lenzetto.

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Medically reviewed by Dr. Liz Andrew

BMS Accredited Menopause Doctor

iconReviewed: 19/02/2025 Published: 21/02/2025
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Oestrogen spray we prescribe

Lenzetto is a body identical oestrogen product which contains small amounts of a natural hormone called estradiol.

It is an easy-to-use, daily spray. You apply it to the forearm or inner thigh, on clean dry skin and it dries quickly. It gradually passes through the skin into your bloodstream where it then travels throughout the body to help with menopause symptoms.

Each device contains 56 sprays but the number of sprays you use each day will depend on the severity of your symptoms and your doctor’s instructions. It can be difficult to know when it runs out, so marking off sprays on the box can be helpful.

Although it dries within around 2 minutes and leaves no residue, women should wait a few minutes before dressing and avoid swimming or bathing within the first few hours of using it. If using sun cream, this must be applied at least an hour before using Lenzetto.

In women who still have a womb, it needs to be used alongside progesterone to provide endometrial protection.

FAQs

Key information about Oestrogen spray

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