Everything you need to know about Estradot
Everything you need to know about Estradot
Estradot is a form of oestrogen replacement therapy used as part of Hormone Replacement Therapy (HRT). It is a transdermal patch, meaning it delivers oestrogen through the skin rather than orally.
If you are considering Estradot as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor

Key information about Estradot
How and where to apply Estradot?
- 1
Directly to skin
Apply directly to skin, replacing twice per week. Apply the patch to a hairless area.
- 2
Apply to the lower abdomen or buttocks
It is important the patch is applied below the waist
- 3
Avoid areas of skin irritation or tight clothing.
Do not apply creams or gels before the patch, as this can affect stickiness
- 4
Change application sites regularly
Rotate application sites to prevent skin irritation.
.png)
Benefits of Estradot
Replacing oestrogen with Estradot can bring many benefits, and have an impact on all 40 symptoms of menopause.
- Supports bone health - reduces the risk of osteoporosis
- Provides a steady release of oestrogen - helping to maintain stable hormone levels
- Bypasses digestion - making it a gentler option for those who experience stomach issues with oral HRT
- Lower risk of blood clots - compared to oral oestrogen

Estradot explained
Dr. Laura Cawley and Dr. Liz Andrew explain Estradot on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.
Estradot is available on our All-in-one plans
Our plans cover appointments, medication and on-going support

Conveniently access care online, from either a doctor or menopause nurse
If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.

Estradot side effects
Common side effects can include:
- Skin irritation on the site which the patch is applied
- Breast tenderness or pain
- Bloating
- Abdominal pain
- Headaches
- Mood changes
Estradot dosages explained
Provides 25mcg of estradiol. This is considered a low dose.
Every 3-4 days
Provides 50mcg of estradiol. This is considered a moderate dose.
Every 3-4 days
Provides 75mcg of estradiol. This is considered a moderate dose.
Every 3-4 days
Provides 100mcg of estradiol. Considered a high dose
Every 3-4 days
As this is a higher dose of oestrogen, higher doses of progesterone are needed, if you still have a womb.








Helpful resources
Explore menopause guidance from our specialists

Signs HRT is not working for you
Understanding how HRT works and what to expect can help manage expectations when you start treatment.

Oestrogen replacement
There are many different types of oestrogen replacement and understanding your options can help you to make the best choice for your health and well-being.

Bio identical vs body identical hormone replacement therapy
This guide looks at the differences between body identical HRT and bioidentical HRT.

HRT and breast cancer
You may be ready to explore treatment options but be worried about the risks of taking hormone-based medications. Read our article about HRT and breast cancer to understand more.
