Everything you need to know about Ovestin (0.1% Estriol cream)
Everything you need to know about Ovestin (0.1% Estriol cream)
Ovestin is a low-dose vaginal oestrogen cream containing estriol, a form of oestrogen that helps restore the vaginal tissues and improve symptoms of vaginal atrophy, dryness, and irritation.
In 2024, Ovestin was rebranded by the manufacturer and is now called 0.1% Estriol Cream. Despite the name change, the formulation remains the same, providing the same benefits for vaginal and urinary symptoms of menopause.
Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor
Reviewed: 18/03/2025 Published: 20/03/2025.png&w=3840&q=100)
Key Information About Ovestin (0.1% Estriol Cream)
How and where to apply Ovestin cream?
- 1
Insert using the applicator
A small amount is inserted into the vagina before bed, usually daily for the first few weeks, then reduced to twice a week for maintenance.
- 2
Can also be used externally
A pea-sized amount can be applied to the vaginal opening or vulva for additional relief.
- 3
Consistency is key
It may take a few weeks to see full benefits.
- 4
Wash hands before and after use
To prevent irritation or transfer.
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Benefits of Ovestin (0.1% Estriol Cream)
- Restores vaginal moisture – reducing dryness, irritation, and discomfort
- Supports bladder health – reducing urinary urgency, frequency, and infections
- Helps with mild prolapse symptoms – by improving vaginal tissue strength
- Can be used long-term – safe for extended use without major systemic effects
- Easy to apply – simple at-home use
Ovestin is available on our Personalised plan
Our plans cover appointments, medication and on-going support
Conveniently access care online, from either a doctor or menopause nurse
If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.
Side effects of Ovestin (0.1% Estriol Cream)
Most women tolerate Ovestin cream well, as it works locally with minimal absorption into the bloodstream. However, like all medications, it can cause side effects, particularly in the first few weeks of use.
Common Side Effects (Usually Settle with Time):
- Mild vaginal irritation (burning, itching, or discharge)
- Breast tenderness
- Headaches
- Bloating or mild stomach discomfort
- Skin irritation if applied externally
Most side effects settle within a few weeks as your body adjusts. If symptoms persist or worsen, speak to your doctor about adjusting your dose or trying an alternative treatment.
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