Everything you need to know about Sandrena Gel

It is applied directly to the skin, allowing oestrogen to be absorbed without passing through the digestive system. This can make it a better option for some women, in particular those who may be experiencing digestive issues or have tried oral HRT and found that it upsets their stomach.

Yes, Sandrena gel is considered safe when prescribed appropriately and used as directed. Like all HRT, it is backed by research and regulated to ensure safety and effectiveness. Using Sandrena through the skin (transdermally) avoids the small risk of blood clots associated with tablet forms of HRT. However, individual risks vary, so it’s important to discuss your medical history with your doctor at Menopause Care, or your GP.

Sandrena gel is body identical. It contains estradiol, which has the same chemical structure as the oestrogen naturally produced by the body. This makes it a well-tolerated option for many women.

If you still have a womb (uterus), then yes, you need to take a separate progestogen to protect the uterine lining. This can be in the form of:

• Micronised progesterone (Utrogestan) – taken orally
• The Mirena coil – which releases progestogen directly into the uterus
• Synthetic progestogen tablets or patches
• If you have had a hysterectomy, you do not need progesterone

There is no strong evidence that Sandrena gel directly causes weight gain. Some women experience temporary fluid retention or bloating, but this often settles with time. Hormonal changes in menopause can naturally lead to a shift in fat distribution, but HRT does not cause fat gain—and for some, it can help maintain muscle mass and metabolism.

Avoid showering, swimming, or vigorous exercise for at least 1 hour after application. This is to ensure that you have given the gel enough time to absorb, and you see the most benefit you can for this treatment.

Yes, all our expert clinicians can prescribe sandrena gel. If you book into a consultation your doctor will review your symptoms and medical history, and talk through your options. Whilst many women do start oestrogen gel through our service, the final prescription decision will be with the prescribing clinician. We can not guarantee any prescriptions.

Yes, Sandrena is available as part of the £90 medication credit on our plans. It’s a common prescription. However, The final prescription decision will be with the prescribing clinician who you have your appointment with. We can not guarantee any specific prescriptions.