Everything you need to know about Androfeme
Everything you need to know about Androfeme
Androfeme is a testosterone replacement therapy designed specifically for women. It is a transdermal cream, meaning it is absorbed through the skin rather than taken orally.
If you are considering Androfeme as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor

Key information about Androfeme
How and where to use Androfeme?
- 1
Choose a consistent application time
Androfeme should be applied once daily, at the same time each day for consistency. It can be used morning or evening, depending on what fits best into your routine.
- 2
Choose where to apply the cream
Androfeme should be applied to a clean, dry, and hair-free area of skin e.g the inner thigh. Some women apply to their forearm, but this can increase the chances of transdermal transfer. Do not apply to your breasts or genitals.
- 3
Measure the correct dose
Use the prescribed amount prescribed by your doctor - usually a pea-sized amount (0.5mL) per day. Massage the cream into the skin until fully absorbed.
- 4
Allow the cream to dry and wash your hands
Wait at least 10 minutes before getting dressed to prevent any cream transferring to your clothing. It is important to avoid washing, showering or swimming for at least 2 hours after applying Androfeme.

Benefits of Androfeme
Replacing testosterone with Androfeme can bring many benefits, particularly for women experiencing these specific symptoms:
- Low libido
- Brain fog
- Low energy

Androfeme explained
Dr. Liz Andrew explains Androfeme on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.
Androfeme is available on our All-in-one plans
Our plans cover appointments, medication and on-going support

Conveniently access care online, from either a doctor or menopause nurse
If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.

Side effects of Androfeme
Common side effects of Androfeme can include:
- Mild increase in facial or body hair (usually fine, light hair and on the application site
- Oily skin or mild acne
- Changes in mood – slight irritability or emotional shifts
- Headaches
Less Common Side Effects of Androfeme are:
- Hair thinning – this is rare but can happen if testosterone levels become too high
- Deepening of the voice – this is very uncommon at the correct female dose
Androfeme dosages explained
Provides 2.5mg testosterone. This is considered a low starting dose.
Applied daily
Provides 5mg testosterone. This is the most common dose for women.
Applied daily
Provides 7.5mg testosterone. This is a higher dose and sometimes used if lower doses are not effective.
Applied daily
Provides 10mg testosterone. This is a high dose which is rarely prescribed.
Applied daily and requires close monitoring.








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