Everything you need to know about Androfeme

Androfeme is a testosterone replacement therapy designed specifically for women. It is a transdermal cream, meaning it is absorbed through the skin rather than taken orally.

If you are considering Androfeme as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

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Medically reviewed by Dr. Liz Andrew

BMS Accredited Doctor

iconReviewed: 24/02/2025 Published: 25/02/2025
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The basics

Key information about Androfeme

4 tips to help you

How and where to use Androfeme?

  • 1

    Choose a consistent application time

    Androfeme should be applied once daily, at the same time each day for consistency. It can be used morning or evening, depending on what fits best into your routine.

  • 2

    Choose where to apply the cream

    Androfeme should be applied to a clean, dry, and hair-free area of skin e.g the inner thigh. Some women apply to their forearm, but this can increase the chances of transdermal transfer. Do not apply to your breasts or genitals.

  • 3

    Measure the correct dose

    Use the prescribed amount prescribed by your doctor - usually a pea-sized amount (0.5mL) per day. Massage the cream into the skin until fully absorbed.

  • 4

    Allow the cream to dry and wash your hands

    Wait at least 10 minutes before getting dressed to prevent any cream transferring to your clothing. It is important to avoid washing, showering or swimming for at least 2 hours after applying Androfeme.

Benefits of Androfeme

Replacing testosterone with Androfeme can bring many benefits, particularly for women experiencing these specific symptoms:

  • Low libido
  • Brain fog
  • Low energy
Book your first consultation

Book a consultation with a menopause specialist, or view our different plans to learn more about what we offer.

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Androfeme explained

Dr. Liz Andrew explains Androfeme on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.

Androfeme is available on our All-in-one plans

Our plans cover appointments, medication and on-going support

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All-in-one plans

Conveniently access care online, from either a doctor or menopause nurse


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Initial appointment online with your specialist (45 minutes)
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Prescribed medication (up to £90 is covered, every 3 months)
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Follow-up appointments with the same specialist every 3 months (30 minutes)
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Support from a personal care coordinator
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Unlimited mentoring sessions
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Flexible to cancel every 3 months
Doctor all-in-one plan
£89 per month
Nurse all-in-one plan
£49 per month
Androfeme with Menopause Care

If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.

Side effects of Androfeme

Common side effects of Androfeme can include:

  • Mild increase in facial or body hair (usually fine, light hair and on the application site
  • Oily skin or mild acne
  • Changes in mood – slight irritability or emotional shifts
  • Headaches

Less Common Side Effects of Androfeme are:

  • Hair thinning – this is rare but can happen if testosterone levels become too high
  • Deepening of the voice – this is very uncommon at the correct female dose

Androfeme dosages explained

Each 1mL of Androfeme contains 10mg of testosterone. The usual prescribed dose is 0.5mL per day, delivering 5mg of testosterone. However, the dose can vary depending on individual needs and doctor recommendations. Always ask your doctor if you have any questions about the dosing.
0.25mL
Dosage level

Provides 2.5mg testosterone. This is considered a low starting dose.

Application frequency

Applied daily

0.5mL
Dosage level

Provides 5mg testosterone. This is the most common dose for women.

Application frequency

Applied daily

0.75mL
Dosage level

Provides 7.5mg testosterone. This is a higher dose and sometimes used if lower doses are not effective.

Application frequency

Applied daily

1mL
Dosage level

Provides 10mg testosterone. This is a high dose which is rarely prescribed.

Application frequency

Applied daily and requires close monitoring.

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Dr. Liz Andrew
Your dosage level of Androfeme can vary depending on the individual. This should be explained clearly by your doctor before starting medication and also throughout your treatment if you are making any adjustments.
Book your first consultation

Book a consultation with a menopause specialist, or view our different plans to learn more about what we offer.

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