Testosterone Treatments/

Everything you need to know about Testogel 40.5mg gel

Testogel 40.5mg Gel is a testosterone replacement therapy used to supplement low testosterone levels. It comes in sachets and is absorbed through the skin as a transdermal gel.

If you are considering Testogel as part of your HRT plan, here is what you need to know about how to use it, its benefits, and possible side effects.

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Medically reviewed by Dr. Liz Andrew

BMS Accredited Doctor

iconReviewed: 24/02/2025 Published: 25/02/2025
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The basics

Key information about Testogel

4 tips to help you

How and where to apply Testogel for women?

  • 1

    Choose a consistent application time

    Testogel should be applied once daily, at the same time each day for consistency. It can be used morning or evening, depending on what fits best into your routine.

  • 2

    Choose where to apply the cream

    Testogel should be applied to a clean, dry, and hair-free area of skin e.g the inner thigh or lower abdomen. Some women apply to their forearm, but this can increase the chances of transdermal transfer. Do not apply to your breasts or genitals.

  • 3

    Measure the correct dose

    Women typically use a pea-sized amount (equivalent to approximately 0.5mL or 2.5mg of testosterone) as prescribed by their doctor. Massage the gel into the skin until fully absorbed.

  • 4

    Allow the gel to dry and wash your hands

    Wait at least 10 minutes before getting dressed to prevent any cream transferring to your clothing. It is important to avoid washing, showering or swimming for at least 2 hours after applying Testogel. Testosterone needs time to fully absorb into the skin. Washing too soon reduces absorption, making the dose less effective. Sweat, soap, and water can remove or dilute the gel.

Benefits of Testogel

Testogel can provide benefits for women experiencing symptoms of low testosterone, particularly during menopause.

In the UK, the guidelines only refer to testosterone treatment being recommended when women have persistent struggles with low libido after trying HRT. There is strong evidence showing that testosterone replacement in menopausal women can:

  • Boost libido – Helps improve sexual desire and responsiveness

There is emerging evidence to suggest that it also helps with:

  • Increased energy levels – Reduces fatigue and enhances overall vitality
  • Enhanced cognitive function – Supports memory, focus, and mental clarity
  • Muscle and bone health – Helps maintain muscle mass and reduces the risk of osteoporosis
  • Mood symptoms – Can reduce feelings of low mood, anxiety, and irritability
Book your first consultation

Book a consultation with a menopause specialist, or view our different plans to learn more about what we offer.

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Testogel explained

Dr. Liz Andrew explains Testogel on one of our latest webinars all about HRT and testosterone products. You can watch the fully recorded webinar on YouTube.

Testogel is available on our All-in-one plans

Our plans cover appointments, medication and on-going support

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All-in-one plans

Conveniently access care online, from either a doctor or menopause nurse


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Initial appointment online with your specialist (45 minutes)
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Prescribed medication (up to £90 is covered, every 3 months)
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Follow-up appointments with the same specialist every 3 months (30 minutes)
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Support from a personal care coordinator
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Unlimited mentoring sessions
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Flexible to cancel every 3 months
Doctor all-in-one plan
£89 per month
Nurse all-in-one plan
£49 per month
Testogel with Menopause Care

If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.

Side effects of Testogel

Common side effects of Androfemme can include:

  • Mild increase in facial or body hair (usually fine, light hair and on the application site
  • Oily skin or mild acne
  • Changes in mood – slight irritability or emotional shifts
  • Headaches
  • Skin irritation at the application site

Less Common Side Effects of Androfemme are:

  • Hair thinning – this is rare but can happen if testosterone levels become too high
  • Deepening of the voice – this is very uncommon at the correct female dose

Testogel dosages explained

Testogel 40.5mg gel comes in individual sachets and is designed for testosterone replacement therapy. Women require a much lower dose than men, and the amount used should be carefully measured. This will involve getting the right amount of Testogel for your prescription out of the sachets (which were designed for male testosterone replacement). Getting the right dose can be really tricky. This is why it is important to have your levels monitored by blood tests as you start.
0.25 sachet
Dosage level

Provides 10mg testosterone. This is considered a high dose.

Application frequency

Applied daily

0.2 sachet
Dosage level

Provides 8mg testosterone. This is considered a moderate dose.

Application frequency

Applied daily

0.15 sachet
Dosage level

Provides 6mg testosterone. This is the moderate-low dose, commonly prescribed for women.

Application frequency

Applied daily

0.1 sachet
Dosage level

Provides 4mg testosterone. This is a low dose, used for maintenance or for women sensitive to testosterone

Application frequency

Applied daily

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Dr. Liz Andrew
Your dosage level of Testogel can vary depending on the individual. This should be explained clearly by your doctor before starting medication and also throughout your treatment if you are making any adjustments.
Book your first consultation

Book a consultation with a menopause specialist, or view our different plans to learn more about what we offer.

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