Everything you need to know about Vagifem pessaries
Everything you need to know about Vagifem pessaries
Vagifem is a local vaginal oestrogen treatment that comes in the form of a pessary (tablet) inserted directly into the vagina. It contains estradiol, a form of oestrogen that helps restore the vaginal tissues and improve symptoms of vaginal atrophy, dryness, and irritation.
Medically reviewed by Dr. Liz Andrew
BMS Accredited Doctor
Reviewed: 14/03/2025 Published: 20/03/2025
Key Information About Vagifem (10mcg Estradiol Pessaries)
How to use Vagifem
- 1
Insert using the applicator
One pessary is inserted into the vagina, usually daily for the first two weeks, then reduced to twice a week for maintenance
- 2
Consistency is key
It may take a few weeks to feel the difference
- 3
Wash hands before and after use
To prevent irritation or transfer
- 4
For vaginal use only
The pessary should never be swallowed
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Benefits of Vagifem
- Restores vaginal moisture – reducing dryness, irritation, and discomfort
- Supports bladder health – reducing urinary urgency, frequency, and infections
- Helps with mild prolapse symptoms – by improving vaginal tissue strength
- Can be used long-term – safe for extended use without major systemic effects
- Easy to apply – simple at-home use with a pre-filled applicator
Vagifem is available on our Personalised plans
Our plans cover appointments, medication and on-going support
Conveniently access care online, from either a doctor or menopause nurse
If you are not a patient with us, but you would like this medication, you will need to book to see one of our expert doctors who will work with you to create a treatment plan.
Vagifem side effects
Most women tolerate Vagifem well, as it works locally with minimal absorption into the bloodstream. However, like all medications, it can cause side effects, particularly in the first few weeks of use.
Common Side Effects (Usually Settle with Time):
- Mild vaginal irritation (burning, itching, or discharge)
- Bloating or mild stomach discomfort
- Spotting or light bleeding (usually in the first few months)
Most side effects settle within a few weeks as your body adjusts. If symptoms persist or worsen, speak to your doctor about adjusting your dose or trying an alternative treatment.
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